The metabolic heterogeneity of rabbit ear cartilage chondroitin sulphate
نویسندگان
چکیده
منابع مشابه
Comparative biochemistry of chondroitin sulphate-proteins of cartilage and notochord.
Fragments that consisted mainly of two polysaccharide chains joined by a short polypeptide bridge (doublets) were prepared from chondroitin sulphate-proteins of lamprey, sturgeon, elasmobranch and ox connective tissues after hydrolysis with trypsin and chymotrypsin. Consideration of molecular parameters, compositions and behaviour on gel electrophoresis and density-gradient fractionation leads ...
متن کاملMultifunctional chondroitin sulphate for cartilage tissue-biomaterial integration.
A biologically active, high-strength tissue adhesive is needed for numerous medical applications in tissue engineering and regenerative medicine. Integration of biomaterials or implants with surrounding native tissue is crucial for both immediate functionality and long-term performance of the tissue. Here, we use the biopolymer chondroitin sulphate (CS), one of the major components of cartilage...
متن کاملThe degradation of cartilage chondroitin sulphate by the chondroitinase of Proteus vulgaris.
Specificity. Pyruvate is reduced at less than 2 % of the rate of an equimolar amount of hydroxypyruvate by this preparation of the enzyme. Since both pyruvate and hydroxypyruvate rapidly oxidize DPNH in the presence of lactic dehydrogenase of muscle, which is obtainable commercially (Boehringer und Soehne, Mannheim), a differential analysis of pyruvate and hydroxypyruvate in mixtures of the two...
متن کاملA preliminary study of the effects of glucosamine sulphate and chondroitin sulphate on surgically treated and untreated focal cartilage damage.
The effects of Glucosamine Sulphate (GS) and Chondroitin Sulphate (CS) on the healing of damaged and repaired articular cartilage were investigated. This study was conducted using 18 New Zealand white rabbits as experimental models. Focal cartilage defects, surgically created in the medial femoral condyle, were either treated by means of autologous chondrocyte implantation (ACI) or left untreat...
متن کاملNature of the interaction of chondroitin 4-sulphate and chondroitin sulphate-proteoglycan with collagen.
The electrostatic interaction of chondroitin sulphate and the chondroitin sulphate-proteoglycan with collagen was studied by chromatography of the glycosaminoglycan and the proteoglycan on a collagen gel. The observed binding between the macromolecules increased with decreasing pH and ionic strength, and was significant under physiological conditions. A study of the interaction between chondroi...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1970
ISSN: 0306-3283
DOI: 10.1042/bj1160329